lines = (line for line in open('/some/file'))
splited_lines = (line.split() for line in lines)

splited_lines = (line.split() for line in open('/some/file'))

def gen(arg):
    for line in arg:
        line_sp = line.split()
        if line_sp[2] == 'var1' and line_sp[3] == 'var2':
            yield line_sp[2:]

text = '''aaaa bbbb cccc dddd
aaaa bbbb var1 var2'''.split('\n')
# case 1
print [i for i in gen(text)]
# case 2
for i in gen(text):
    print i

[i for i in gen(text)]