from PyQt4 import QtCore, QtGui
class AnyWidget(QtGui.QWidget):
    def __init__(self):
        QtGui.QWidget.__init__(self)
        self.initUI()


    def initUI(self):
        boxlay = QtGui.QHBoxLayout(self)
        frame = QtGui.QFrame(self)
        frame.setFrameShape(QtGui.QFrame.StyledPanel)
        frame.setFrameShadow(QtGui.QFrame.Raised)

        gridlay = QtGui.QGridLayout(frame)

        label = QtGui.QLabel("label",frame)
        gridlay.addWidget(label,0,0)

        hellobutton = QtGui.QPushButton("Hello",None)
        gridlay.addWidget(hellobutton,0,1)

        self.connect(hellobutton, QtCore.SIGNAL("clicked()"), self._printtext)

        boxlay.addWidget(frame)

    def _printtext(self):
        self.label.setText('was pressed')


if __name__=="__main__":
    app = QtGui.QApplication(sys.argv)
    aw = AnyWidget()
    aw.show()
    sys.exit(app.exec_())

self.label = QtGui.QLabel("label",frame)